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Chemical Structure : K-Ras G12C-IN-12
CAS No.: 1469337-95-8
Catalog No.: PC-45536Not For Human Use, Lab Use Only.
An allosteric inhibitor of oncogenic K-Ras(G12C) with EC50 of 0.32 uM in H1792 cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $152 | In stock | |
| 50 mg | $600 | In stock |
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An allosteric inhibitor of oncogenic K-Ras(G12C) with EC50 of 0.32 uM in H1792 cells; relys on the mutant cysteine for binding and therefore do not affect the wild-type K-Ras.
| M.Wt | 449.6713 | |
| Formula | C15H17ClIN3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 48 mg/mL |
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| Chemical Name/SMILES |
2-Propen-1-one, 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl]-1-piperazinyl]- |
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1. Ostrem JM, et al. Nature. 2013 Nov 28;503(7477):548-51.
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