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Chemical Structure : KDM4/5 inhibitor 19a
Catalog No.: PC-22360Not For Human Use, Lab Use Only.
KDM4/5 inhibitor 19a is a potent, cell penetrant, dual KDM4/5-subfamily inhibitor with Ki values of 4 nM/7 nM for KDM4A/KDM5B, respectively.
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KDM4/5 inhibitor 19a is a potent, cell penetrant, dual KDM4/5-subfamily inhibitor with Ki values of 4 nM/7 nM for KDM4A/KDM5B, respectively.
KDM4/5 inhibitor 19a potently inhibits KDM4A, KDM4B, KDM5B and KDM5C with IC50 of 0.1, 0.043, 0.038 and 0.123 uM, respectively.
| M.Wt | 426.52 | |
| Formula | C25H26N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yann-Vaï Le Bihan, et al. Eur J Med Chem. 2019 Sep 1:177:316-337.
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