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Chemical Structure : KDM5A covalent inhibitor N73
Catalog No.: PC-35801Not For Human Use, Lab Use Only.
KDM5A covalent inhibitor N73 is the the isopropyl ester derivative of N71, an irreversible KDM5A inhibitor (IC50=0.22 uM) that covalently interacts with Cys481, >20-fold selectivity over KDM4A..
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KDM5A covalent inhibitor N73 is the the isopropyl ester derivative of N71, an irreversible KDM5A inhibitor (IC50=0.22 uM) that covalently interacts with Cys481, >20-fold selectivity over KDM4A.
| M.Wt | 564.745 | |
| Formula | C31H40N4O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Horton JR, et al. J Med Chem. 2018 Nov 15. doi: 10.1021/acs.jmedchem.8b01219.
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