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Chemical Structure : KDM5A inhibitor compound 1
Catalog No.: PC-20354Not For Human Use, Lab Use Only.
KDM5A inhibitor compound 1 (ZINC33576) is a potent, selective KDM5A (JARID1A) inhibitor with IC50 of 23.8 nM.
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KDM5A inhibitor compound 1 (ZINC33576) is a potent, selective KDM5A (JARID1A) inhibitor with IC50 of 23.8 nM.
KDM5A inhibitor compound 1 (ZINC33576) displays high selectivity for KDM5A over both KDM4A (IC50>100 uM) and other KDM5 family members (KDM5B and KDM5C).
KDM5A inhibitor compound 1 (ZINC33576) is highly potent cytotoxicity to KDM5A-overexpressing breast cancer cell lines (MDA-MB-231 cell, IC50=0.54 uM).
| M.Wt | 402.40 | |
| Formula | C20H22N2O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Guan-Jun Yang, et al. Cancers (Basel). 2019 Jan 15;11(1):92.
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