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Chemical Structure : KH7
CAS No.: 330676-02-3
Catalog No.: PC-60892Not For Human Use, Lab Use Only.
KH7 is a potent, specific soluble adenylyl cyclase (sAC) inhibitor that inhibits Mn2+-dependent sAC with IC50 of 2.7 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $248 | In stock | |
| 25 mg | $398 | In stock | |
| 50 mg | $588 | In stock | |
| 100 mg | Get quote |
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KH7 is a potent, specific soluble adenylyl cyclase (sAC) inhibitor that inhibits Mn2+-dependent sAC with IC50 of 2.7 uM.
KH7 inhibits physiologically stimulated sAC with similar potency with IC50 of 8.0 uM.
KH7 completely blocks the capacitation-induced rise in cAMP in wild-type sperm at 10 uM, inhibits in vitro fertilization.
| M.Wt | 419.297 | |
| Formula | C17H15BrN4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(E)-2-((1H-benzo[d]imidazol-2-yl)thio)-N'-(5-bromo-2-hydroxybenzylidene)propanehydrazide |
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1. Bitterman JL, et al. J Pharmacol Exp Ther. 2013 Dec;347(3):589-98.
2. Hess KC, et al. Dev Cell. 2005 Aug;9(2):249-59.
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