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Chemical Structure : KHKI-01128
Catalog No.: PC-22622Not For Human Use, Lab Use Only.
KHKI-01128 is a highly potent NUAK family kinase 2 (NUAK2) inhibitor with IC50 of 24 nM.
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KHKI-01128 is a highly potent NUAK family kinase 2 (NUAK2) inhibitor with IC50 of 24 nM.
KHKI-01128 suppresses cell proliferation IC50 of 1.26 μM, and induces apoptosis of SW480 cells.
KHKI-01128 effectively suppresses the expression of YES1-associated transcriptional regulator (YAP) target genes.
| M.Wt | 582.63 | |
| Formula | C29H33F3N8O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Seung Hyeong Lee, et al. Anticancer Res. 2024 Jul;44(7):2909-2919.
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