Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Cytoskeleton/Cell Adhesion Molecules-Kinesin-KIF18A inhibitor compound 3
KIF18A inhibitor compound 3

Chemical Structure : KIF18A inhibitor compound 3

CAS No.: 2446613-56-3

Add to Favorites

KIF18A inhibitor compound 3

Catalog No.: PC-22245Not For Human Use, Lab Use Only.

KIF18A inhibitor compound 3 is a potent, selective mitotic kinesin KIF18A inhibitor of IC50 of 8.2 nM, inhibits KIF18A's microtubule-stimulated ATPase activity.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
250 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

KIF18A inhibitor compound 3 is a potent, selective mitotic kinesin KIF18A inhibitor of IC50 of 8.2 nM, inhibits KIF18A's microtubule-stimulated ATPase activity.

Physicochemical Properties

M.Wt 565.64
Formula C25H33F2N7O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-6-((2-hydroxyethyl)sulfonamido)-4-(6-azaspiro[2.5]octan-6-yl)nicotinamide

References

1. Schutt KL, et al. Front Mol Biosci. 2024 Feb 12;11:1328077.

2. Tamayo N. A., et al. J. Med. Chem. 65, 4972–4990.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: