Catalog No.: PC-47079Not For Human Use, Lab Use Only.
KIRA6 is a potent, ATP-competitive type II IRE1α kinase inhibitor, allosterically inhibits IRE1α RNase kinase activity with IC50 of 0.6 uM and prevents oligomerization.
KIRA6 is a potent, ATP-competitive type II IRE1α kinase inhibitor, allosterically inhibits IRE1α RNase kinase activity with IC50 of 0.6 uM and prevents oligomerization.
KIRA6 inhibits IRE1α in vivo and to promote cell survival under ER stress, preserve photoreceptor functional viability in rat models of ER stress-induced retinal degeneration.
