KIRA9 | IRE1α inhibitor | Probechem Biochemicals

Chemical Structure : KIRA9

Catalog No.: PC-49056Not For Human Use, Lab Use Only.

KIRA9 is a potent inhibitor of IRE1α RNase activity with IC50 of 39 nM, blocks ER-localized mRNA decay and apoptosis.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

KIRA9 is a potent inhibitor of IRE1α RNase activity with IC50 of 39 nM, blocks ER-localized mRNA decay and apoptosis.

M.Wt	572.607
Formula	C27H27F3N6O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-Propanesulfonamide, 3,3,3-trifluoro-N-[4-[[3-[2-[(3S)-3-piperidinylamino]-4-pyrimidinyl]-2-pyridinyl]oxy]-1-naphthalenyl]-

1. Feldman HC, et al. Nat Chem Biol. 2021 Nov;17(11):1148-1156.