KM-001 | TRPV3 inhibitor | Probechem Biochemicals

Chemical Structure : KM-001

KM-001 (KM001)

Catalog No.: PC-27645Not For Human Use, Lab Use Only.

KM-001 is a potent, specific TRPV3 inhibitor/antagonist, suppresses 2-APB (50 μM)-induced Ca2+ influx in HEK-293 cells transiently transfected with hTRPV3 with IC50 of 0.26 μM.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

KM-001 is a potent, specific TRPV3 inhibitor/antagonist, suppresses 2-APB (50 μM)-induced Ca2+ influx in HEK-293 cells transiently transfected with hTRPV3 with IC50 of 0.26 μM.

Physicochemical Properties

M.Wt	416.50
Formula	C26H25FN2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3-(2'-cyclopropyl-3-(hydroxymethyl)-[1,1'-biphenyl]-4-yl)pyrrolidin-1-yl)(5-fluoropyridin-2-yl)methanone

References

1. Wang Y, et al. EMBO J. 2026 Aug 13. doi: 10.1038/s44318-026-00896-9.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

KM-001 (KM001)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.