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Chemical Structure : KP-1019 sodium salt
Catalog No.: PC-60226Not For Human Use, Lab Use Only.
A ruthenium complex anticancer agent that is useful for metastatic tumors and cis-platin resistant tumors.
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A ruthenium complex anticancer agent that is useful for metastatic tumors and cis-platin resistant tumors; dose dependently inhibites ATPase activity of P-glycoprotein (P-gp) with Ki of 31 uM; potently blocks P-glycoprotein-mediated rhodamine 123 efflux under serum-free conditions (EC50=8 uM); induces DNA damage, leading to cell cycle delay and cell death in Saccharomyces cerevisiae.
Solid Tumors
Phase 1 Discontinued
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| Appearance | Solid | |
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10 mM in DMSO |
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