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Chemical Structure : KPT-8602 Z-isomer
CAS No.: 1642300-78-4
Catalog No.: PC-42151Not For Human Use, Lab Use Only.
KPT-8602 Z-isomer is the Z-isomer of Eltanexor (KPT-8602), which is a second-generation SINE with markedly reduced brain penetration compared to selinexor.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $238 | In stock | |
| 10 mg | $368 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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KPT-8602 Z-isomer is the Z-isomer of Eltanexor (KPT-8602), which is a second-generation SINE with markedly reduced brain penetration compared to selinexor.
| M.Wt | 428.2913 | |
| Formula | C17H10F6N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO |
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| Chemical Name/SMILES |
5-Pyrimidineacetamide, α-[[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]methylene]-, (αZ)- |
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1. Etchin J, et al. Leukemia. 2017 Jan;31(1):143-150.
2. Hing ZA, et al. Leukemia. 2016 Dec;30(12):2364-2372.
3. Vercruysse T, et al. Clin Cancer Res. 2017 May 15;23(10):2528-2541.
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