| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-35933 |
Verdinexor
|
1392136-43-4 |
Verdinexor (KPT-335, KPT335) is an orally bioavailable, selective inhibitor of nuclear export (SINE), inhibits the function of nuclear export protein Exportin 1 (XPO1/CRM1) and the viability of Jurkat and canine DLBCL cells with IC50 of 8.7 nM and 13.3 nM, respectively. |
| PC-61270 |
KPT-251
|
1388841-50-6 |
KPT-251 (KPT251) is a small-molecule, selective inhibitor of nuclear export (CRM1 inhibitor, SINE) that exhibits potent antileukemic activity. |
| PC-35581 |
Selinexor
|
1393477-72-9 |
Selinexor (KPT-330, KPT330) is a potent, orally available, selective inhibitor of nuclear export (SINE) targeting CRM1 (XPO1). |
| PC-70229 |
Leptomycin B
|
87081-35-4 |
A potent and specific nuclear export inhibitor that binds to and inhibits CRM1 (XPO1). |
| PC-42151 |
KPT-8602 Z-isomer
|
1642300-78-4 |
The Z-isomer of Eltanexor (KPT-8602), which is a second-generation SINE with markedly reduced brain penetration compared to selinexor.. |
| PC-42150 |
Eltanexor
|
1642300-52-4 |
A second-generation SINE, orally bioavailable Exportin 1 (XPO1,CRM1) inhibitor with markedly reduced brain penetration compared to selinexor (30-fold less). |
