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Request The Product List ofExportin-1 (CRM1,XPO1) Exportin-1 (CRM1,XPO1)

Cat. No. Product Name CAS No. Information
PC-35933

Verdinexor

1392136-43-4 Verdinexor (KPT-335, KPT335) is an orally bioavailable, selective inhibitor of nuclear export (SINE), inhibits the function of nuclear export protein Exportin 1 (XPO1/CRM1) and the viability of Jurkat and canine DLBCL cells with IC50 of 8.7 nM and 13.3 nM, respectively.
PC-61270

KPT-251

1388841-50-6 KPT-251 (KPT251) is a small-molecule, selective inhibitor of nuclear export (CRM1 inhibitor, SINE) that exhibits potent antileukemic activity.
PC-35581

Selinexor

1393477-72-9 Selinexor (KPT-330, KPT330) is a potent, orally available, selective inhibitor of nuclear export (SINE) targeting CRM1 (XPO1).
PC-70229

Leptomycin B

87081-35-4 A potent and specific nuclear export inhibitor that binds to and inhibits CRM1 (XPO1).
PC-42151

KPT-8602 Z-isomer

1642300-78-4 The Z-isomer of Eltanexor (KPT-8602), which is a second-generation SINE with markedly reduced brain penetration compared to selinexor..
PC-42150

Eltanexor

1642300-52-4 A second-generation SINE, orally bioavailable Exportin 1 (XPO1,CRM1) inhibitor with markedly reduced brain penetration compared to selinexor (30-fold less).

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