KR-40795 | Autotaxin inhibitor | Probechem Biochemicals

Chemical Structure : KR-40795

Catalog No.: PC-23311Not For Human Use, Lab Use Only.

KR-40795 is a novel small molecule autotaxin (ATX) inhibitor with IC50 of 0.13 uM, binds to the allosteric tunnel and hydrophobic pocket of ATX.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

KR-40795 is a novel small molecule autotaxin (ATX) inhibitor with IC50 of 0.13 uM, binds to the allosteric tunnel and hydrophobic pocket of ATX.

M.Wt	461.90
Formula	C26H20ClNO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	methyl (Z)-4-((2-((1-(3-chlorophenyl)-2,5-dioxopyrrolidin-3-ylidene)methyl)phenoxy)methyl)benzoate

1. Hyeong Lee S, et al. Bioorg Med Chem Lett. 2024 Oct 28:130006.