KRAS G12C inhibitor 1 |CAS:1698023-15-2 Probechem Biochemicals

Chemical Structure : KRAS G12C inhibitor 1

KRAS G12C inhibitor 1

Catalog No.: PC-61203Not For Human Use, Lab Use Only.

KRAS G12C inhibitor 1 is a potent, selective, covalent KRAS G12C inhibitor that selectively inhibit KRAS G12C-dependent signaling and cancer cell growth at sub-micromolar concentrations.

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Biological Activity

KRAS G12C inhibitor 1 is a potent, selective, covalent KRAS G12C inhibitor that selectively inhibit KRAS G12C-dependent signaling and cancer cell growth at sub-micromolar concentrations.

Physicochemical Properties

M.Wt	396.85
Formula	C21H18ClFN4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-(6-chloro-7-(2-fluorophenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

References

1. Zeng M, et al. Cell Chem Biol. 2017 Aug 17;24(8):1005-1016.e3.

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