KRas-IN-1 |CAS:84783-01-7 Probechem Biochemicals

Chemical Structure : KRas-IN-1

CAS No.: 84783-01-7

KRas-IN-1

Catalog No.: PC-45517Not For Human Use, Lab Use Only.

A chemical fragment hit that binds to K-Ras (G12D) with affinities of 1.3-2 mM.

Packing	Price	Stock	Quantity
10 mg	$400	In stock
50 mg	$1200	In stock

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Biological Activity

A chemical fragment hit that binds to K-Ras (G12D) with affinities of 1.3-2 mM; binds to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure.

Physicochemical Properties

M.Wt	207.292
Formula	C11H13NOS
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: ≥ 28 mg/mL
Chemical Name/SMILES	Methanethione, (2-hydroxyphenyl)-1-pyrrolidinyl-

References

1. Sun Q, et al. Angew Chem Int Ed Engl. 2012 Jun 18;51(25):6140-3.

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KRas-IN-1

Biological Activity

Physicochemical Properties

References

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