KS176 | BCRP inhibitor | Probechem Biochemicals

Chemical Structure : KS176

CAS No.: 1253452-78-6

KS176 (KS 176, KS-176)

Catalog No.: PC-45706Not For Human Use, Lab Use Only.

KS176 is a potent and selective inhibitor of BCRP multidrug transporter with IC50 of 0.59 and 1.39 uM in Pheo A and Hoechst 33342 assays, respectively.

Packing	Price	Stock
5 mg	$78	In stock
10 mg	$118	In stock
25 mg	$198	In stock
50 mg	$298	In stock
100 mg	$488	In stock
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Biological Activity

KS176 is a potent and selective inhibitor of BCRP multidrug transporter with IC50 of 0.59 and 1.39 uM in Pheo A and Hoechst 33342 assays, respectively.
KS176 displays no inhibitory activity against P-gp or MRP1.

Physicochemical Properties

M.Wt	405.4034
Formula	C22H19N3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 35 mg/mL
Chemical Name/SMILES	Benzamide, N-[4-(2-hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]-

References

1. Pick A, et al. ChemMedChem. 2010 Sep 3;5(9):1498-505.

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KS176 (KS 176, KS-176)

Biological Activity

Physicochemical Properties

References

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