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KS176

Chemical Structure : KS176

CAS No.: 1253452-78-6

KS176 (KS 176, KS-176)

Catalog No.: PC-45706Not For Human Use, Lab Use Only.

KS176 is a potent and selective inhibitor of BCRP multidrug transporter with IC50 of 0.59 and 1.39 uM in Pheo A and Hoechst 33342 assays, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

KS176 is a potent and selective inhibitor of BCRP multidrug transporter with IC50 of 0.59 and 1.39 uM in Pheo A and Hoechst 33342 assays, respectively.
KS176 displays no inhibitory activity against P-gp or MRP1.

Physicochemical Properties

M.Wt 405.4034
Formula C22H19N3O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
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Solubility

DMSO: ≥ 35 mg/mL

Chemical Name/SMILES

Benzamide, N-[4-(2-hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]-

References

1. Pick A, et al. ChemMedChem. 2010 Sep 3;5(9):1498-505.

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