KUNG29 | Grp94 inhibitor | Probechem Biochemicals

Chemical Structure : KUNG29

KUNG29 (KUNG-29, KUNG 29)

Catalog No.: PC-60159Not For Human Use, Lab Use Only.

KUNG29 is a potent, selective Grp94 inhibitor with Kd of 0.2 uM.

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Biological Activity

KUNG29 is a potent, selective Grp94 inhibitor with Kd of 0.2 uM.
KUNG29 displays 40-fold selecticity over Hsp90α.
KUNG29 induces the degradation of integrin α2 in MDA-MB-231 cells.

Physicochemical Properties

M.Wt	430.89
Formula	C22H23ClN2O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methyl 3-Chloro-2-(2-(1-(2-ethoxybenzyl)-1H-imidazol-2-yl)-ethyl)-4,6-dihydroxybenzoate

References

1. Crowley VM, et al. J Med Chem. 2016 Apr 14;59(7):3471-88.

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KUNG29 (KUNG-29, KUNG 29)

Biological Activity

Physicochemical Properties

References

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