KUNG38 | Grp94 inhibitor | Probechem Biochemicals

Chemical Structure : KUNG38

KUNG38 (KUNG-38, KUNG 38)

Catalog No.: PC-60158Not For Human Use, Lab Use Only.

KUNG38 is a potent, selective Grp94 inhibitor with Kd of 0.44 uM.

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Biological Activity

KUNG38 is a potent, selective Grp94 inhibitor with Kd of 0.44 uM.
KUNG38 displays 19-fold selecticity over Hsp90α.
KUNG38 induces the degradation of integrin α2 in MDA-MB-231 cells.

Physicochemical Properties

M.Wt	411.24
Formula	C18H16Cl2N2O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methyl 3-Chloro-2-(2-(1-((5-chlorofuran-2-yl)methyl)-1H-imidazol-2-yl)ethyl)-4,6-dihydroxybenzoate

References

1. Crowley VM, et al. J Med Chem. 2016 Apr 14;59(7):3471-88.

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KUNG38 (KUNG-38, KUNG 38)

Biological Activity

Physicochemical Properties

References

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