L-338192 |CAS:1421702-02-4 Probechem Biochemicals

Chemical Structure : L-338192

L-338192 (L338192)

Catalog No.: PC-61808Not For Human Use, Lab Use Only.

L-338192 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 29 uM in AlphaScreen assay.

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Biological Activity

L-338192 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 29 uM in AlphaScreen assay.
L-338192 displays 4.8-fold and 3.8-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.

Physicochemical Properties

M.Wt	353.407
Formula	C15H15NO5S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-3-(5-(2,3-dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid

References

1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11.

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L-338192 (L338192)

Biological Activity

Physicochemical Properties

References

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