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Request The Product List ofBeta-catenin Beta-catenin

Cat. No. Product Name CAS No. Information
PC-35350

SKL2001

909089-13-0 SKL2001 is a specific small molecule activator (agonist) of the Wnt/β-catenin pathway, stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction.
PC-35329

E-7386

1799824-08-0 E-7386 (E7386) is a potent, orally active modulator of CBP/beta-catenin, disrupts the interaction and inhibits canonical Wnt signaling pathway /TCF reporter gene activity in LiCl-stimulated HEK-293 and MDA-MB-231 with IC50 of 55 and 73 nM, respectively.
PC-61323

Carnosic acid

3650-09-7 Carnosic acid (Carnosate) is a naturally occurring phenolic compound with antioxidant, anti-inflammatory and antimicrobial properties, inhibits the BCL9/β-catenin interaction with Ki of 3.3 uM.
PC-61288

Tegatrabetan

1227637-23-1 Tegatrabetan (BC-2059, BC2059, Tegavivint) is an orally bioavailable β-catenin antagonist that disrupts the binding of β-catenin to TBL1 and promotes β-catenin degradation, attenuates nuclear and cytoplasmic levels of β-catenin.
PC-70120

PRI-724

847591-62-2 PRI-724 (PRI724) is a potent, specific, second generation CBP/beta-catenin antagonist with IC50 of 150 nM, an isomer or enantiomer of ICG-001.
PC-70092

KYA-1797K

1956356-56-1 A derivative of KY1220 with improved inhibitory activity for Wnt/β-catenin signaling.
PC-70091

KY-1220

292168-79-7 KY-1220 is a small molecule destabilizer of both β-catenin and Ras via inhibition of the Wnt/β-catenin pathway (IC50=2.1 uM).

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