Chemical Structure : Zolucatetide
CAS No.:
3044032-95-0
Zolucatetide
(FOG-001, I-66)
Catalog No. : PC-27045Not For Human Use, Lab Use Only.
Zolucatetide (FOG-001, I-66) is a potent β-catenin inhibitor with IC50 of <50 nM, inhibits β-catenin and T-cell factor (TCF) transcription factor PPI, inhibits cell proliferation and induces cell cycle arrest in target cells.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2704501
Biological Activity
Zolucatetide (FOG-001, I-66) is a potent β-catenin inhibitor with IC50 of <50 nM, inhibits β-catenin and T-cell factor (TCF) transcription factor PPI, inhibits cell proliferation and induces cell cycle arrest in target cells.
Physicochemical Properties
M.Wt
2076.42
Formula
C102H134N18O25S2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
L-Alaninamide, 12,42-(2Z)-2-hexene-1,6-diyl-1-acetyl-L-prolyl-L-α-aspartyl-4-methyl-L-leucyl-(2S,6E)-2-amino-10-(carboxyoxy)-6-decenoyl-L-α-aspartyl-3-carboxy-L-phenylalanyl-2-methylalanyl-L-alanyl-L-phenylalanyl-L-lysyl-(3S)-3-amino-3-pyrrolidinecarbonyl-3-(3-thienyl)-L-alanyl-3-benzo[b]thien-3-yl-L-alanyl-L-α-glutamyl-, (4→11),(14→10)-dilactam
References
1. Patent WO2022261257A1.
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