Cat. No. |
Product Name |
Information |
PC-20622 |
ICG-001
TCF/beta-catenin inhibitor
|
ICG-001 (ICG001) is a specific small molecule inhibitor of TCF/beta-catenin, antagonizes β-catenin/TCF-mediated transcription with IC50 of 3 uM. |
PC-20582 |
HI-B1
β-catenin/TCF4 inhibitor
|
HI-B1 is a small molecule inhibitor of β-catenin/TCF4 interaction, directly targets β-catenin and disrupts β-catenin/TCF4 complex formation. |
PC-20175 |
IMU1003
Wnt/β-catenin inhibitor
|
IMU1003 (IMU-1003) is a small molecule inhibitor of Wnt/β-catenin signaling, decreases β-catenin levels and inhibits target gene expression that promotes cancer cell proliferation. |
PC-38652 |
PTK7/β-catenin inhibitor 01065
PTK7/β-catenin inhibitor
|
PTK7/β-catenin inhibitor 01065 is a small molecule inhibitor of PTK7/β-catenin interaction (IC50=8.9 uM) targeting the Wnt pathway signaling, induces antiproliferative and antitumor effects in vitro in CRC cells harboring β-catenin or adenomatous polyposis coli (APC) mutations. |
PC-38567 |
E722-2648
β-catenin/BCL9 inhibitor
|
E722-2648 (Compound C-1) is a novel specific and competitive small molecule β-catenin/BCL9 interaction inhibitor with ITC KD of 1.05 uM and IC50 of 9 uM, blocks oncogenic Wnt signaling and disrupts cholesterol homeostasis in colorectal cancer. |
PC-72072 |
β-catenin inhibitor C2
β-catenin inhibitor
|
β-catenin inhibitor C2 is a novel potent selective β-catenin inhibitor with Kd of 54.96 nM, directly to ARM domain of β-catenin. |
PC-62707 |
β-catenin-IN-11a
|
β-catenin-IN-11a is a β-catenin/CD44/Nanog axis inhibitor, docks into the β-catenin allosteric site and interferes β-catenin/TCF-4 complex. |
PC-61802 |
β-catenin-IN-37
|
β-catenin-IN-37 is a novel potent, and selective small-molecule inhibitor for the β-catenin/Tcf4 protein-protein interaction with Ki of 17 uM. |