| Cat. No. |
Product Name |
Information |
| PC-42398 |
LF3
β-catenin/TCF4 inhibitor
|
A small-molecule antagonist of the β-catenin/TCF4 interaction with IC50 of 1.65 and 1.82 uM in AlphaScreen and ELISA assay, respectively. |
| PC-42676 |
IQ-1
p300/β-catenin inhibitor
|
A small molecule, specific inhibitor of p300/β-catenin interaction that binds to PR72/130 subunit of PP2A. |
| PC-42324 |
PNU-74654
Tcf/β-catenin inhibitor
|
PNU-74654 (PNU74654) is a potent Wnt/beta-catenin inhibitor by disrupting Tcf/β-catenin interaction binds to β-catenin with Kd of 450 nM. |
| PC-45815 |
Triptonide
beta-catenin inhibitor
|
Triptonide (NSC 165677, PG 492) is a key bioactive small molecule identified in Tripterygium wilfordii Hook F., has a broad spectrum of biological functions, inhibits canonical Wnt/β-catenin signaling by targeting β-catenin. |
| PC-44658 |
FH535
PPARγ/δ inhibitor
|
FH535 is a potent, dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment, inhibits the Wnt/β-catenin pathway. |
| PC-22501 |
NF764
β-catenin degrader
|
NF764 is a potent and selective, covalent β-catenin (CTNNB1) binder and degrader wtih DC50 of 3.5 nM in HT29 cells (Emax=85%), targeting C619 of CTNNB1. |
| PC-22500 |
β-catenin degrader EN83
β-catenin degrader
|
β-catenin degrader EN83 is a covalent degrader of β-catenin (CTNNB1), depletes CTNNB1 in a ubiquitin-proteasome-dependent manner. |
| PC-20622 |
ICG-001
TCF/beta-catenin inhibitor
|
ICG-001 (ICG001) is a specific small molecule inhibitor of TCF/beta-catenin, antagonizes β-catenin/TCF-mediated transcription with IC50 of 3 uM. |
| PC-20582 |
HI-B1
β-catenin/TCF4 inhibitor
|
HI-B1 is a small molecule inhibitor of β-catenin/TCF4 interaction, directly targets β-catenin and disrupts β-catenin/TCF4 complex formation. |
