| Cat. No. |
Product Name |
Information |
| PC-35329 |
E-7386
CBP/beta-catenin inhibitor
|
E-7386 (E7386) is a potent, orally active modulator of CBP/beta-catenin, disrupts the interaction and inhibits canonical Wnt signaling pathway /TCF reporter gene activity in LiCl-stimulated HEK-293 and MDA-MB-231 with IC50 of 55 and 73 nM, respectively. |
| PC-62707 |
β-catenin-IN-11a
β-catenin inhibitor
|
β-catenin-IN-11a is a β-catenin/CD44/Nanog axis inhibitor, docks into the β-catenin allosteric site and interferes β-catenin/TCF-4 complex. |
| PC-62168 |
CCT-031374
beta-catenin inhibitor
|
CCT-031374 (CCT031374) is a selective β-catenin signaling inhibitor with IC50 of 6.1 uM. |
| PC-62166 |
iCRT3
β-catenin responsive transcription inhibitor
|
iCRT-3 is a selective, cell-permeable β-catenin responsive transcription (CRT) inhibitor with IC50 of 8.2 nM. |
| PC-62165 |
iCRT5
β-catenin responsive transcription inhibitor
|
iCRT5 is a selective, cell-permeable β-catenin responsive transcription (CRT) inhibitor with IC50 of 18 nM. |
| PC-61811 |
BC-21
β-catenin/TCF4 inhibitor
|
BC-21 (NSC 109268) is a novel small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 6.55 uM. |
| PC-61810 |
ZTM000990
β-catenin/TCF4 inhibitor
|
ZTM000990 is a small-molecule antagonist of the oncogenic Tcf4/β-catenin protein complex with IC50 of 0.64 uM. |
| PC-61809 |
CWP-232228
β-catenin/TCF4 inhibitor
|
CWP-232228 is a highly potent small-molecule Wnt/β-catenin signaling inhibitor that targets the β-catenin/Tcf4 interaction in the nucleus. |
| PC-61808 |
L-338192
β-catenin/TCF4 inhibitor
|
L-338192 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 29 uM in AlphaScreen assay. |
| PC-61807 |
R-360163
β-catenin/TCF4 inhibitor
|
R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay. |
| PC-61806 |
R-999636
β-catenin/TCF4 inhibitor
|
R-999636 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 8.8 uM in FP assay. |
| PC-61805 |
T-155535
β-catenin/TCF4 inhibitor
|
T-155535 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 21 uM in AlphaScreen assay. |
