T-155535 |CAS:925001-05-4 Probechem Biochemicals

Chemical Structure : T-155535

T-155535 (T155535)

Catalog No.: PC-61805Not For Human Use, Lab Use Only.

T-155535 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 21 uM in AlphaScreen assay.

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Biological Activity

T-155535 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 21 uM in AlphaScreen assay.
T-155535 displays 2.8-fold and 5.2-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.

Physicochemical Properties

M.Wt	315.709
Formula	C16H10ClNO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(4-(4-chlorophenoxy)phenyl)isoxazole-3-carboxylic acid

References

1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11.

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T-155535 (T155535)

Biological Activity

Physicochemical Properties

References

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