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T-155535

Chemical Structure : T-155535

CAS No.: 925001-05-4

T-155535 (T155535)

Catalog No.: PC-61805Not For Human Use, Lab Use Only.

T-155535 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 21 uM in AlphaScreen assay.

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    Biological Activity

    T-155535 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 21 uM in AlphaScreen assay.
    T-155535 displays 2.8-fold and 5.2-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.

    Physicochemical Properties

    M.Wt 315.709
    Formula C16H10ClNO4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    5-(4-(4-chlorophenoxy)phenyl)isoxazole-3-carboxylic acid

    References

    1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11.

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