R-360163 |CAS:883791-50-2 Probechem Biochemicals

Chemical Structure : R-360163

R-360163 (R360163)

Catalog No.: PC-61807Not For Human Use, Lab Use Only.

R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay.

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Biological Activity

R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay.
R-360163 displays 16-fold and 25-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.

Physicochemical Properties

M.Wt	392.371
Formula	C20H16N4O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-3-(2-(2-(1-allyl-2-oxoindolin-3-ylidene)hydrazinyl)-2-oxoacetamido)benzoic acid

References

1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11.

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R-360163 (R360163)

Biological Activity

Physicochemical Properties

References

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