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Chemical Structure : R-999636
Catalog No.: PC-61806Not For Human Use, Lab Use Only.
R-999636 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 8.8 uM in FP assay.
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R-999636 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 8.8 uM in FP assay.
R-999636 displays 5.8-fold and 7.8-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.
| M.Wt | 395.239 | |
| Formula | C21H12Cl2N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11.
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