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Chemical Structure : L-870810
Catalog No.: PC-70242Not For Human Use, Lab Use Only.
A potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties.
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L-870810 is a potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties.
L-870810 exhibits broad-spectrum activity against WT and multidrug-resistant HIV-1, HIV-2, and SIV; orally bioavailable.
| M.Wt | 430.454 | |
| Formula | C20H19FN4O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hazuda DJ, et al. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11233-8.
2. Zeng LF, et al. J Med Chem. 2012 Nov 26;55(22):9492-509.
3. Hombrouck A, et al. Antimicrob Agents Chemother. 2008 Jun;52(6):2069-78.
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