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L759-0762

Chemical Structure : L759-0762

CAS No.: 1112447-35-4

L759-0762

Catalog No.: PC-28805Not For Human Use, Lab Use Only.

L759-0762 is a small molecule RNA-binding motif protein 41 (RBM41) inhibitor, disrupts the interaction between RBM41 and CKMT1B mRNA, selectively sensitizes TSCC cells to disulfidptosis under glucose deprivation by abolishing the protective function of RBM41.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

L759-0762 is a small molecule RNA-binding motif protein 41 (RBM41) inhibitor, disrupts the interaction between RBM41 and CKMT1B mRNA, selectively sensitizes TSCC cells to disulfidptosis under glucose deprivation by abolishing the protective function of RBM41.

Physicochemical Properties

M.Wt 452.49
Formula C26H21FN6O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-2-[4-(pyridin-2-yl)piperazin-1-yl]quinoline

References

1. Tao B, et al. Cell Death Dis. 2026 Jul 31;17(1):914.

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