LC-1028 |CAS 2324158-08-7 Probechem Biochemicals

Chemical Structure : LC-1028

LC-1028 (LC1028;LC 1028)

Catalog No.: PC-36136Not For Human Use, Lab Use Only.

LC-1028 (LC1028) is a novel potent selective, covalent and irreversible inhibitor of p97 (valosin-containing protein), remains essentially irreversible ac tivity against p97 mutant C522A..

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Biological Activity

(LC1028) is a novel potent selective, covalent and irreversible inhibitor of p97 (valosin-containing protein), remains essentially irreversible aciivity against p97 mutant C522A.

Physicochemical Properties

M.Wt	449.558
Formula	C28H27N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1-(4-(Benzylamino)-5,6,7,8-tetrahydroquinazolin-2-yl)-2-methyl-1H-indol-4-yl)but-2-ynamide

References

1. Ding R, et al. J Med Chem. 2019 Mar 14;62(5):2814-2829.

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LC-1028 (LC1028;LC 1028)

Biological Activity

Physicochemical Properties

References

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