LC-YD17

Chemical Structure : LC-YD17

Catalog No.: PC-27974Not For Human Use, Lab Use Only.

LC-YD17 is a potent, selective YTH domain-containing protein 1 (YTHDC1) inhibitor with IC50 of 107.12 nM, exhibits growth inhibitory activity in MOLM-13 and THP-1 cells with IC50 of 11.74 and 16.36 uM respectively.

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Biological Activity

LC-YD17 is a potent, selective YTH domain-containing protein 1 (YTHDC1) inhibitor with IC50 of 107.12 nM, exhibits growth inhibitory activity in MOLM-13 and THP-1 cells with IC50 of 11.74 and 16.36 uM respectively.

Physicochemical Properties

M.Wt	465.95
Formula	C22H24ClN9O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-(4-((2-chloro-6-(methylamino)-9H-purin-9-yl)methyl)-1H-1,2,3-triazol-1-yl)phenyl)-1-(piperidin-1-yl)ethan-1-one

References

1. Mingchen Wang, et al. Adv Sci (Weinh). 2026 Aug 27:e77386.

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LC-YD17

Biological Activity

Physicochemical Properties

References

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