LDC3140 | CDK7 inhibitor | Probechem Biochemicals

Chemical Structure : LDC3140

Catalog No.: PC-21922Not For Human Use, Lab Use Only.

LDC3140 is a potent, selective CDK7 inhibitor with IC50 of <5 nM, >500-fold selective over CDK1/2/4/6/9.

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Biological Activity

LDC3140 is a potent, selective CDK7 inhibitor with IC50 of <5 nM, >500-fold selective over CDK1/2/4/6/9.

M.Wt	423.57
Formula	C23H33N7O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-(dimethylamino)benzyl)-8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-amine

1. Kelso TW, et al. Mol Cell Biol. 2014 Oct 1;34(19):3675-88.