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LDHA inhibitor 1g

Chemical Structure : LDHA inhibitor 1g

CAS No.: 862719-04-8

LDHA inhibitor 1g

Catalog No.: PC-23596Not For Human Use, Lab Use Only.

LDHA inhibitor 1g is a potent, selective inhibitor of lactate dehydrogenase A (LDHA) with IC50 of 25 nM, without affecting the LDH-B isoform (LDHB), inhibits the aerobic glycolytic phenotype of cancer metabolism.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LDHA inhibitor 1g is a potent, selective inhibitor of lactate dehydrogenase A (LDHA) with IC50 of 25 nM, without affecting the LDH-B isoform (LDHB), inhibits the aerobic glycolytic phenotype of cancer metabolism.

Physicochemical Properties

M.Wt 384.27
Formula C17H22BrNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

methyl 4-bromo-3-[(n-hexyloxy)methyl]-1-hydroxy-1H-indole-2-carboxylate

References

1. Cheon SY, et al. Eur J Med Chem. 2024 Nov 30;283:117104.

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