Cat. No. |
Product Name |
Information |
PC-72514 |
AXKO-0046
LDHB inhibitor
|
AXKO-0046 (AXKO0046) is the first highly selective, small molecule inhibitor of human lactate dehydrogenase B (LDHB), exhibits uncompetitive LDHB inhibition with EC50 of 42 nM. |
PC-62683 |
LDHA-IN-104
LDHA inhibitor
|
LDHA-IN-104 is a potent and selective lactate dehydrogenase A (LDHA) inhibitor with IC50 of 0.87 uM, less potent for LDHB (IC50=6.9 uM). |
PC-62049 |
FX-11
LDHA inhibitor
|
FX-11 (LDHA inhibitor FX11) is a cell permeable, selective, reversible, NADH competitive inhibitor of lactate dehydrogenase A (LDHA) with Ki of 50 nM (LDHA subunit M), less potent for LDHB or pLDH. |
PC-61222 |
GSK 2837808A
LDHA inhibitor
|
GSK 2837808A is a potent, specific, NADH-competitive lactate dehydrogenase-A (LDH-A) inhibitor with IC50 of 2.6 nM, >10-fold selectivity over LDHB. |
PC-42245 |
GNE-140 racemate
Lactate dehydrogenase inhibitor
|
GNE-140 racemate is the racemate of GNE-140, a novel potent, selective lactate dehydrogenase (LDH) inhibitor with IC50 of 3, 5, and 5 nM for LDHA, LDHB, and LDHC, respectively. |
PC-42247 |
(S)-GNE-140
|
The less active enantiomer of GNE-140, inhibits LDHA activity (18-fold less potent that (R)-GNE-140). |
PC-42246 |
(R)-GNE-140
Lactate dehydrogenase inhibitor
|
(R)-GNE-140 (GNE-140) is a novel potent, selective lactate dehydrogenase (LDH) inhibitor with IC50 of 3, 5, and 5 nM for LDHA, LDHB, and LDHC, respectively. |