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LDN-109657

Chemical Structure : LDN-109657

CAS No.: 438488-97-2

LDN-109657 (LDN109657)

Catalog No.: PC-61637Not For Human Use, Lab Use Only.

LDN-109657 is a novel SMN2 modulator that increase SMN protein levels in 3813 fibroblasts by twofold at 370 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    LDN-109657 is a novel SMN2 modulator that increase SMN protein levels in 3813 fibroblasts by twofold at 370 nM.

    Physicochemical Properties

    M.Wt 344.429
    Formula C18H20N2O3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-cyclopentyl-1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide

    References

    1. Cherry JJ, et al. EMBO Mol Med. 2013 Jul;5(7):1103-18.

    2. Cherry JJ, et al. J Biomol Screen. 2012 Apr;17(4):481-95.

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