LDN-109657 | SMN2 modulator | Probechem Biochemicals

Chemical Structure : LDN-109657

Catalog No.: PC-61637Not For Human Use, Lab Use Only.

LDN-109657 is a novel SMN2 modulator that increase SMN protein levels in 3813 fibroblasts by twofold at 370 nM.

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Biological Activity

LDN-109657 is a novel SMN2 modulator that increase SMN protein levels in 3813 fibroblasts by twofold at 370 nM.

M.Wt	344.429
Formula	C18H20N2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-cyclopentyl-1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide

1. Cherry JJ, et al. EMBO Mol Med. 2013 Jul;5(7):1103-18.

2. Cherry JJ, et al. J Biomol Screen. 2012 Apr;17(4):481-95.