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LEM-06

Chemical Structure : LEM-06

CAS No.: 1212675-57-4

LEM-06 (LEM06)

Catalog No.: PC-28089Not For Human Use, Lab Use Only.

LEM-06 is a small molecule inhibitor of histone methyltransferase NSD2 with IC50 of 0.8 mM against H3K36 methylation in vitro.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LEM-06 is a small molecule inhibitor of histone methyltransferase NSD2 with IC50 of 0.8 mM against H3K36 methylation in vitro.

Physicochemical Properties

M.Wt 490.65
Formula C29H38N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R,5S)-3-(1-acetylpiperidin-4-yl)-9-(2-(morpholinomethyl)phenyl)-1,2,3,4,5,6-hexahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one

References

1. Eric di Luccio. J Cancer Prev. 2015 Jun;20(2):113-20.

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