LHC165 | TLR7 agonist | Probechem Biochemicals

Chemical Structure : LHC165

LHC165 (LHC-165)

Catalog No.: PC-22807Not For Human Use, Lab Use Only.

LHC165 is a potent, selective TLR7 agonist, generates effective tumor antigen-specific T-cell adaptive immune response as well as durable antitumor responses.

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Biological Activity

LHC165 is a potent, selective TLR7 agonist, generates effective tumor antigen-specific T-cell adaptive immune response as well as durable antitumor responses.

Physicochemical Properties

M.Wt	603.56
Formula	C29H32F2N3O7P
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzo[f][1,7]naphthyridine-8-propanoic acid, 5-amino-2-[2-[4-[2-(3,3-difluoro-3-phosphonopropoxy)ethoxy]-2-methylphenyl]ethyl]-

References

1. Zawit M, et al. Ann Transl Med. 2021 Jun;9(12):1038.

2. Jonathan A. Deane, et al. Cancer Res (2019) 79 (13_Supplement): 4128.

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LHC165 (LHC-165)

Biological Activity

Physicochemical Properties

References

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