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LHC165

Chemical Structure : LHC165

CAS No.: 1258595-14-0

LHC165 (LHC-165)

Catalog No.: PC-22807Not For Human Use, Lab Use Only.

LHC165 is a potent, selective TLR7 agonist, generates effective tumor antigen-specific T-cell adaptive immune response as well as durable antitumor responses.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LHC165 is a potent, selective TLR7 agonist, generates effective tumor antigen-specific T-cell adaptive immune response as well as durable antitumor responses.

Physicochemical Properties

M.Wt 603.56
Formula C29H32F2N3O7P
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzo[f][1,7]naphthyridine-8-propanoic acid, 5-amino-2-[2-[4-[2-(3,3-difluoro-3-phosphonopropoxy)ethoxy]-2-methylphenyl]ethyl]-

References

1. Zawit M, et al. Ann Transl Med. 2021 Jun;9(12):1038.

2. Jonathan A. Deane, et al. Cancer Res (2019) 79 (13_Supplement): 4128.

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