LIH383 | ACKR3 agonist | Probechem Biochemicals

Chemical Structure : LIH383

LIH383 (LIH-383, FGGFMRRK-NH2)

Catalog No.: PC-22933Not For Human Use, Lab Use Only.

LIH383 is a potent, selective atypical chemokine receptor ACKR3 (CXCR7) agonist with EC50 of 0.61 nM in inducing β-arrestin recruitment to ACKR3.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

LIH383 is a potent, selective atypical chemokine receptor ACKR3 (CXCR7) agonist with EC50 of 0.61 nM in inducing β-arrestin recruitment to ACKR3.
LIH383 competed directly with CXCL12-AF647 for ACKR3 binding at low nanomolar concentrations.
LIH383 shows equivalent activity on human and mouse ACKR3 (mACKR3).
LIH383 is more potent in inducing β-arrestin recruitment to ACKR3 than the full-length chemokine ligands CXCL12 or CXCL11 (EC50 =1.2 nM and 2.2 nM, respectively).

Physicochemical Properties

M.Wt	997.24
Formula	C45H72N16O8S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Phe-Gly-Gly-Phe-Met-Arg-Arg-Lys-NH2

References

1. Max Meyrath, et al. Nat Commun. 2020 Jun 19;11(1):3033.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

LIH383 (LIH-383, FGGFMRRK-NH2)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.