Chemical Structure : LIN28 inhibitor LI71
Catalog No.: PC-35201Not For Human Use, Lab Use Only.
LIN28 inhibitor LI71 is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 7 uM, binds the cold shock domain to suppress LIN28's activity against let-7 in leukemia cells and embryonic stem cells. .
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LIN28 inhibitor LI71 is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 7 uM, binds the cold shock domain to suppress LIN28's activity against let-7 in leukemia cells and embryonic stem cells.
M.Wt | 335.403 | |
Formula | C21H21NO3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Wang L, et al. Cell Rep. 2018 Jun 5;23(10):3091-3101.
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