LMD-009 | CCR8 agonist | Probechem Biochemicals

Chemical Structure : LMD-009

CAS No.: 950195-51-4

LMD-009 (LMD 009, LMD009)

Catalog No.: PC-60972Not For Human Use, Lab Use Only.

LMD-009 (LMD 009, LMD009) is a potent, selective, nonpeptide CCR8 agonist that stimulates CCR8-mediated chemotaxis, inositol phosphate accumulation and calcium release with EC50 of 11-87 nM.

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Biological Activity

LMD-009 (LMD 009, LMD009) is a potent, selective, nonpeptide CCR8 agonist that stimulates CCR8-mediated chemotaxis, inositol phosphate accumulation and calcium release with EC50 of 11-87 nM.
LMD-009 displays no activity against other chemokine receptors.

Physicochemical Properties

M.Wt	471.601
Formula	C29H33N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-[3-(2-methoxyphenoxy)benzyl]-1-phenethyl-1,3,8-triaza-spiro[4.5]decan-4-one

References

1. Jensen PC, et al. Mol Pharmacol. 2007 Aug;72(2):327-40.

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LMD-009 (LMD 009, LMD009)

Biological Activity

Physicochemical Properties

References

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