LMPTP inhibitor 5d

Chemical Structure : LMPTP inhibitor 5d

Catalog No.: PC-21978Not For Human Use, Lab Use Only.

LMPTP inhibitor 5d is a potent, selective low molecular weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 20 nM, >1000-fold selective over other phosphatases.

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Biological Activity

LMPTP inhibitor 5d is a potent, selective, uncompetitive low molecular weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 20 nM, >1000-fold selective over other phosphatases.

Physicochemical Properties

M.Wt	384.26
Formula	C19H15Cl2N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(2,6-dichlorobenzyl)-8-(o-tolyl)-3H-purin-6-amine

References

1. Stanford SM, et al. J Med Chem. 2021 May 13;64(9):5645-5653.

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