LN-439A

Chemical Structure : LN-439A

Catalog No.: PC-23140Not For Human Use, Lab Use Only.

LN-439A is a small molecule BRCA1-associated protein 1 (BAP1) inhibitor by binding to the catalytic pocket of BAP1, leading to the ubiquitination and degradation of Krüppel-like factor 5 (KLF5), inhibits proliferation and migration of BLBC cells.

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Biological Activity

Physicochemical Properties

M.Wt	439.49
Formula	C24H26FN3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-(2-fluorophenyl)acetyl)-N-(2-(2-hydroxyethoxy)ethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-8-carboxamide

References

1. Wang TT, et al. Acta Pharmacol Sin. 2024 Oct 8. doi: 10.1038/s41401-024-01361-1.

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LN-439A

Biological Activity

Physicochemical Properties

References

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