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Chemical Structure : LN6023
Catalog No.: PC-49368Not For Human Use, Lab Use Only.
LN6023 (LN-6023) a potent, selective and first-in-class inhibitor of the atypical chemokine receptor 3 (ACKR3, CXCR7) with β-arrestin EC50 of 3.5 uM.
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LN6023 (LN-6023) a potent, selective and first-in-class inhibitor of the atypical chemokine receptor 3 (ACKR3, CXCR7) with β-arrestin EC50 of 3.5 uM.
LN6023 effectively reduced P-selectin expression by up to 97% in a platelet degranulation assay, showed potential for the treatment of platelet-mediated thrombosis.
| M.Wt | 420.576 | |
| Formula | C20H32N6O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Alp Bayrak, et al. Journal of Medicinal Chemistry 2022.
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