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Chemical Structure : LP-403812
Catalog No.: PC-21227Not For Human Use, Lab Use Only.
LP-403812 is a specific small molecule inhibitor of mammalian proline transporter (PROT), inhibits PROT-mediated proline uptake with IC50 of 0.1 uM on both recombinant human and mouse PROT.
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LP-403812 is a specific small molecule inhibitor of mammalian proline transporter (PROT), inhibits PROT-mediated proline uptake with IC50 of 0.1 uM on both recombinant human and mouse PROT.
LP-403812 shows no significant inhibition of glycine and dopamine transporters at concentrations up to 10 uM.
LP-403812 inhibits proline transporter activity of mouse brain synaptosomes with the same potency.
| M.Wt | 494.66 | |
| Formula | C26H34N6O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Xuan-Chuan Yu, et al. Neurosci Lett. 2009 Feb 27;451(3):212-6.
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