LRRK2 G2019S inhibitor 17

Chemical Structure : LRRK2 G2019S inhibitor 17

Catalog No.: PC-27142Not For Human Use, Lab Use Only.

LRRK2 G2019S inhibitor 17 is a potent, selective dual inhibitor of LRRK2 G2019S and JNK3 with IC50 of 3.9 and 22.1 nM.

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Biological Activity

LRRK2 G2019S inhibitor 17 is a potent, selective dual inhibitor of LRRK2 G2019S and JNK3 with IC50 of 3.9 and 22.1 nM.

M.Wt	426.91
Formula	C21H23ClN6O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(N(C)CCCCNC1=NC2=NC3=C1C(Cl)=CN3)C4=CC(N2)=C(OC5CC5)C=C4

1. Kim K, et al. J Med Chem. 2026 Jun 22. doi: 10.1021/acs.jmedchem.6c01439.