Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : LRRK2 inhibitor 25
Catalog No.: PC-49823Not For Human Use, Lab Use Only.
LRRK2 inhibitor 25 is a potent, selective, CNS-penetrant and ATP competitive LRRK2 inhibitor with biochemical IC50 of 0.9 nM, cellular IC50 of 0.3 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | Get quote | ||
| 250 mg | Get quote | ||
| 500 mg | Get quote | ||
| 1 g | Get quote | ||
| 5 g | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
LRRK2 inhibitor 25 is a potent, selective, CNS-penetrant and ATP competitive LRRK2 inhibitor with biochemical IC50 of 0.9 nM, cellular IC50 of 0.3 nM.
LRRK2 inhibitor 25 demonstrated exceptional on-target potency in human peripheral blood mononuclear cells, excellent off-target kinase selectivity, and good brain exposure in rats.
| M.Wt | 414.51 | |
| Formula | C24H26N6O | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. David A Candito, et al. J Med Chem. 2022 Dec 22;65(24):16801-16817.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
