LSD1 inhibitor CHBH

Chemical Structure : LSD1 inhibitor CHBH

Catalog No.: PC-27603Not For Human Use, Lab Use Only.

CHBH is a lysine-specific histone demethylase 1A (LSD1, KDM1A) inhibitor, does not act on KDM4A, reduces the viability of a panel of cancer cell lines with IC50 values in the micromolar range.

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Biological Activity

CHBH is a lysine-specific histone demethylase 1A (LSD1, KDM1A) inhibitor, does not act on KDM4A, reduces the viability of a panel of cancer cell lines with IC50 values in the micromolar range.

Physicochemical Properties

M.Wt	274.70
Formula	C14H11ClN2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-3-chloro-N'-(2-hydroxybenzylidene)benzohydrazide

References

1. Venkataswamy Sorna, et al. J Med Chem. 2013 Dec 12;56(23):9496-508.

2. Federica Sarno, et al. Front Pharmacol. 2018 Sep 7:9:1006.

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