LSN3374443 | Lp(a) formation inhibitor

Chemical Structure : LSN3374443

LSN3374443 (LSN-3374443)

Catalog No.: PC-24909Not For Human Use, Lab Use Only.

LSN3374443 is a potent, dimeric apolipoprotein(a) (apo(a)) binder and inhibitor of Lipoprotein(a) (Lp(a)) formation, disrupts the formation of Lp(a) with IC50 of 36 nM in in vitro Lp(a) assembly assays.

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Biological Activity

Physicochemical Properties

M.Wt	409.49
Formula	C23H27N3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-3-(3-(3-(3-methoxyphenyl)-2-oxoimidazolidin-1-yl)phenyl)-2-((R)-pyrrolidin-3-yl)propanoic acid

References

1. Nuria Diaz, et al. Nature. 2024 May;629(8013):945-950.

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LSN3374443 (LSN-3374443)

Biological Activity

Physicochemical Properties

References

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