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LY2794193

Chemical Structure : LY2794193

CAS No.: 2173037-97-1

LY2794193 (LY 2794193)

Catalog No.: PC-63236Not For Human Use, Lab Use Only.

LY2794193 is a highly potent and selective mGlu3 receptor agonist with Ki of 0.93 nM and EC50 of 47 nM, >100-fold selectivity over mGlu2 receptor..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LY2794193 is a highly potent and selective mGlu3 receptor agonist with Ki of 0.93 nM and EC50 of 47 nM, >100-fold selectivity over mGlu2 receptor.

Physicochemical Properties

M.Wt 334.328
Formula C16H18N2O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1S,2S,4S,5R,6S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid

References

1. Monn JA, et al. J Med Chem. 2018 Mar 22;61(6):2303-2328.

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