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LY2979165

Chemical Structure : LY2979165

CAS No.: 311385-35-9

LY2979165 (MP-101, LY-2979165)

Catalog No.: PC-62593Not For Human Use, Lab Use Only.

LY2979165 (MP-101) is the alanine prodrug of LY2812223, a selective orthosteric mGlu2 receptor agonist.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

LY2979165 (MP-101) is the alanine prodrug of LY2812223, a selective orthosteric mGlu2 receptor agonist.
LY2979165 suppresses glutamate release at presynaptic receptors during periods of enhanced, abnormal, glutamate activity and has potential for use in treating psychiatric and neurologic disorders

Physicochemical Properties

M.Wt 355.369
Formula C13H17N5O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R,2S,4R,5R,6R)-4-((4H-1,2,4-triazol-3-yl)thio)-2-((S)-2-aminopropanamido)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid

References

1. McColm J, et al. Br J Clin Pharmacol. 2017 Aug;83(8):1654-1667.

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